Nootropil 800 mg: Enhance Cognitive Function and Memory Support
| Product dosage: 800mg | |||
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Synonyms
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Nootropil 800 mg contains the active substance piracetam, a well-established nootropic agent belonging to the racetam class. It is primarily indicated for the management of cortical myoclonus and as adjunctive therapy for a range of cognitive disorders. This medication works by modulating neurotransmission, improving neuronal plasticity, and enhancing cerebral microcirculation, offering a targeted approach to support brain function in specific clinical contexts. Its 800 mg tablet formulation provides a convenient dosage option for maintenance therapy.
Features
- Active ingredient: Piracetam 800 mg per tablet
- Pharmaceutical form: Film-coated tablet
- Mechanism: Modulates glutamate and acetylcholine receptors; enhances neuronal membrane fluidity
- Half-life: Approximately 5 hours
- Excretion: Primarily renal, unchanged
- Prescription status: Available by prescription in most jurisdictions
Benefits
- Supports improvement in learning capacity and memory consolidation in cognitively impaired patients
- May reduce the frequency and severity of myoclonic jerks in cortical myoclonus
- Enhances interhemispheric communication via the corpus callosum
- Contributes to neuroprotection under hypoxic conditions
- Aids in the recovery of cognitive function post-cerebral injury
- Provides a well-tolerated option for long-term neurological support
Common use
Nootropil 800 mg is clinically employed for two principal indications. First, it is used in the treatment of cortical myoclonus, either as monotherapy or in combination with other anticonvulsants. Second, it is utilized as an adjunctive therapy for cognitive disorders, such as those associated with aging, post-stroke recovery, or mild cognitive impairment. Off-label, it is sometimes used in contexts requiring cognitive enhancement, though such use should be carefully evaluated by a healthcare provider against evidence and risk.
Dosage and direction
For cortical myoclonus, the initial adult dosage is typically 7.2 g daily, divided into two or three doses, which may be titrated upward by 4.8 g per day every three to four days, to a maximum of 24 g daily. The 800 mg tablets allow for flexible dosing within this range. For cognitive disorders, dosages generally range from 2.4 g to 4.8 g daily, divided into two or three administrations. Tablets should be swallowed whole with liquid, with or without food. Dosage must be individualized based on renal function, clinical response, and tolerability. Always follow the precise instructions of the prescribing physician.
Precautions
Use with caution in patients with a history of haemorrhagic diathesis or those undergoing major surgery. Renal impairment requires dosage adjustment, as piracetam is excreted renally. Periodic monitoring of renal function is advised during long-term therapy. Discontinuation should be gradual to avoid withdrawal symptoms, especially in patients with epilepsy. Not recommended during pregnancy or lactation unless clearly necessary. Patients should avoid activities requiring mental alertness, such as driving, until they know how the medication affects them.
Contraindications
Nootropil is contraindicated in patients with known hypersensitivity to piracetam or any excipients in the formulation. It is also contraindicated in those with severe renal impairment (creatinine clearance <20 mL/min) and in patients with cerebral haemorrhage. It should not be used in individuals with Huntington’s chorea due to risk of exacerbating symptoms.
Possible side effect
Common side effects (≥1/100 to <1/10) include nervousness, weight gain, somnolence, depression, and hyperkinesia. Uncommon side effects (≥1/1,000 to <1/100) may include asthenia, insomnia, headache, dizziness, nausea, vomiting, diarrhoea, abdominal pain, and rash. Rare cases of severe hypersensitivity reactions, including angioedema and anaphylaxis, have been reported. Most adverse reactions are dose-dependent and reversible upon dose reduction or discontinuation.
Drug interaction
Piracetam may potentiate the effects of central nervous system depressants, including alcohol, benzodiazepines, and barbiturates. Concurrent use with thyroid hormone extracts may increase restlessness, irritability, and sleep disturbance. Caution is advised when co-administering with anticoagulants or antiplatelet agents due to a theoretical increased bleeding risk. No significant interactions with cytochrome P450 enzymes are known.
Missed dose
If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next scheduled dose. In that case, skip the missed dose and resume the usual dosing schedule. Do not double the dose to make up for a missed one. Maintaining consistent plasma levels is important for efficacy, particularly in the management of myoclonus.
Overdose
Symptoms of overdose may include severe diarrhoea, abdominal pain, and marked nervousness or agitation. In cases of significant overdose, lethargy and fainting have been reported. There is no specific antidote. Treatment is symptomatic and supportive. Gastric lavage may be considered if ingestion was recent. Haemodialysis is effective in removing piracetam from the bloodstream due to its low molecular weight and minimal protein binding.
Storage
Store in the original container below 30°C (86°F). Protect from light and moisture. Keep out of reach of children and pets. Do not use after the expiration date printed on the packaging.
Disclaimer
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or medication. Do not disregard professional medical advice or delay in seeking it because of something you have read here.
Reviews
Clinical studies and patient reports generally indicate that Nootropil 800 mg is effective in reducing myoclonic jerks and providing modest cognitive benefits in indicated populations. Many users note improved clarity and recall over time, though individual responses can vary. Tolerance is typically good, with side effects often being mild and transient when they occur. It is emphasized that results are best achieved under medical supervision and as part of a comprehensive therapeutic plan.