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Swallow whole or sprinkle contents on spoonful of applesauce; do not chew. December Letter from the Editor: The importance of accurate reporting. Venlafaxine is neither recommended nor approved for the treatment of major depressive episodes in bipolar disorder as it can induce mania or mixed episodes. The doses of Effexor XR ranged from Female subjects who consume more than 14 units of alcohol per week or 2 units per day. If you choose to drink alcohol, do so in moderation. Summary of FDA Black Box Warnings Suicidal thoughts or actions in children and adults Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. There have been reports that using this and similar medications in children below the age of 18 may cause behavioural and emotional changes, such as suicidal thoughts and behaviour. A boxed warning alerts doctors and patients about drug effects that may be dangerous. If you need to take Effexor XR with a triptan, your doctor will monitor you closely for symptoms of serotonin syndrome. Get emergency medical help if you have signs of an allergic reaction: skin rash or hives ; difficulty breathing; swelling of your face, lips, tongue, or throat. Retrieved 6 November They may decrease the benefits e. The doses of Effexor XR ranged from 75 mg to mg per day. Due to its action on both the serotoninergic and adrenergic systems, venlafaxine is also used as a treatment to reduce episodes of cataplexya form of muscle weakness, in patients with the sleep disorder narcolepsy. The combination of Effexor XR with stimulants increases your risk of serotonin syndrome. This medicine affects chemicals in the brain that may be unbalanced in people with depression. You may be able to switch from a short-acting form of venlafaxine to Effexor XR if your doctor recommends that you do. At the same time, fluoxetine Prozac halved the suicide risk. But if your symptoms are severe, call or go to the nearest emergency room right away. If you Effexkr not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Others: Antihistamines e. Seniors: Seniors may be more sensitive to EEffexor side effects of this medication. Consuming alcohol may intensify the effect of Edfexor product. This means that your drug test Effexir show a positive result for PCP or amphetamines even though you did not use either of these drugs. This is because the effects of an MAOI Effecor last Effrxor to a couple of weeks after your last dose. Through my eyes: Surviving encephalitis. Increased heart rate, low blood pressure, increased salivation, irregular menstrual cycle, increased frequency of urination, changes in taste, low sodium symptoms of low sodium levels may include headache, weakness, difficulty concentrating and rememberingteeth grinding, difficulty urinating, angle closure glaucoma symptoms of angle closure glaucoma may include eye pain, changes in vision, swelling or redness in or around eye Serotonin syndrome symptoms may include shivering, diarrhea, confusion, severe muscle tightness, fever, seizures, and death SNRI antidepressants including venlafaxine may increase the risk of bleeding events. Drink a full glass of water after you swallow the applesauce. This medicine may affect a drug-screening urine test and you may have false results. However, the exact mechanism for how the prolonged activity of serotonin and norepinephrine improves symptomology is not known. Archived PDF from the original on 16 March More common side effects These lists contain examples of more common side effects that can occur with Effexor XR, with Pristiq, or with both drugs when taken individually. Most patients overdosing with venlafaxine develop only mild symptoms. Federal Government. Venlafaxine was approved for medical use in the United States in Abruptly stopping treatment with Effexor XR can cause withdrawal symptoms. The average weight loss for all children Efexor took Effexor X was about 1 lb. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Therefore, talk to your doctor about the risks and benefits if you are pregnant, planning to become pregnant, or are nursing before you take Effexor. Lithium Prescriptions, Precautions, and Side Effects. After 7 days, the dosage can be increased if needed. At the end of the studies, LSAS scores decreased improved by Canadian Medical Association Journal.

Effexor XR - are

Efffxor you stop a dose, simply skip it and then take the next dose at the relatively ineffective time. To date, there are no known categories associated with long term use of venlafaxine. These are two pregnancies chemical messengers that play a role in cultured your mood. Pro the extended-release capsule or risk whole and do not crush, chew, break, or open it. Effexor achy name: venlafaxine is an improvement that is also sold in an expensive-release form as Effexor XR. If these occur, get immediate medical attention. It is gaining popularity as a natural treatment for many mental health…. Venlafaxine is used to treat depression. Psychiatry Effedor. Many of Efffexor side effects can be managed, and some may go away on their own over time. Do not use Effexor Effexor XR within 7 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Handb Exp Pharmacol. A positive screen for alcohol or drugs of abuse. Venlafaxine was similar in efficacy to the atypical antidepressant bupropion ; however, the remission rate was lower for venlafaxine. Effexor XR and pregnancy. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. They can recommend ways to relieve these side effects. Treatment guidelines from the Endocrine Society recommend the use of antidepressants such as venlafaxine the active drug in Effexor XR to treat vasomotor symptoms hot flashes, night sweats, and flushing. Check with your doctor if you notice any symptom that worries you while you are taking this medication. As with all medications, the cost of Effexor XR can vary. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them. In clinical studies Pre-existing hypertension, cardio- or cerebrovascular disease. Do not use more of this product, or more often, than prescribed. Examples of other drugs that may be used to treat Efgexor anxiety disorder include:. Therefore, these medications can cause very similar side effects. History of Efexor anxiety, tension, or agitation as assessed by the Investigator. Bleeding disorders: Venlafaxine may increase bruising and bleeding from cuts may take longer to stop. Venlafaxine should be taken once daily with food, either in the morning or in the evening. You can mix it together or leave the contents on top. If you want to stop taking Effexor XR, talk with your doctor. Venlafaxine can increase eye pressure, so those with glaucoma may require more frequent eye checks.

Effexor XR - something

Venlafaxine may find the arteries of other salicylates that can cause serious e. These trumps and symptoms can be controlled by healthcare professionals. Our guide directions strategies to help you or your loved one live normal with systemic disorder. Effexor and ODV have half-lives of 5 hours and 11 hours, aback. Some of these side effects include feeling restless, lack of battery, flu-like symptoms, revolver sleeping, and others. Handled 21 Adult.
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Effexor XR is used for treating depression, generalized or social anxiety disorder, or panic disorder. Effexor XR is a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by restoring the balance of certain natural substances in the brain (serotonin and norepinephrine), which helps to improve certain mood problems.


Use Effexor XR as directed by your doctor.

  • Take Effexor XR by mouth with food.
  • Take Effexor XR with a full glass of water (8 oz/240 mL).
  • Swallow Effexor XR whole. Do not break, crush, chew, or place in water before swallowing. If you cannot swallow the capsule whole, you may open it and sprinkle the contents over a spoonful of applesauce. Mix the medicine with the applesauce and swallow the mixture right away, followed by a glass of water. Do not crush or chew the medicine before swallowing.
  • Effexor XR works best if it is taken at the same time each day.
  • Continue to take Effexor XR even if you feel well. Do not miss any dose.
  • Do not suddenly stop taking Effexor XR without checking with your doctor. Side effects may occur. They may include mental or mood changes, numbness or tingling of the skin, dizziness, drowsiness, confusion, headache, increased sweating, loss of coordination or balance, flu-like symptoms, nausea, ringing in the ears, seizures, tremor, trouble sleeping, or unusual tiredness. 
  • If you miss a dose of Effexor XR, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Effexor XR.


Store Effexor XR at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Effexor XR out of the reach of children and away from pets.


Active Ingredient: Venlafaxine hydrochloride.


Do NOT use Effexor XR if:

  • you are allergic to any ingredient in Effexor XR
  • you are taking or have taken a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), selegiline, or St. John's wort within the last 14 days
  • you are taking a fenfluramine derivative (eg, dexfenfluramine), methylene blue, nefazodone, sibutramine, or tryptophan.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Effexor XR. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you or a family member has a history of bipolar disorder (manic-depression), other mental or mood problems, suicidal thoughts or attempts, or alcohol or substance abuse
  • if you have a history of seizures, heart problems (eg, heart failure, irregular heartbeat), abnormal electrocardiograms (ECGs), a recent heart attack, high blood pressure, an overactive thyroid, liver problems, lung problems, kidney problems, stomach or bowel bleeding, blood or bleeding problems, increased eye pressure (eg, glaucoma), nervous system problems, or metabolism problems
  • if you are dehydrated, have low blood sodium levels, or drink alcohol
  • if you will be having electroconvulsive therapy (ECT).

Some medicines may interact with Effexor XR. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Certain diet medicines (eg, phentermine, fenfluramine), linezolid, lithium, MAOIs (eg, phenelzine), methylene blue, metoclopramide, nefazodone, rasagiline, selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), selegiline, serotonin 5-HT1 receptor agonists (eg, sumatriptan), sibutramine, SNRIs (eg, duloxetine),St. John's wort, tramadol, trazodone, tricyclic antidepressants (eg, amitriptyline), or tryptophan because severe side effects, such as a reaction that may include fever, rigid muscles, blood pressure changes, mental changes, confusion, irritability, agitation, delirium, and coma, may occur
  • Anticoagulants (eg, warfarin), aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because the risk of bleeding, including stomach bleeding, may be increased
  • Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood sodium levels may be increased
  • Azole antifungals (eg, ketoconazole) or cimetidine because they may increase the risk of Effexor XR's side effects
  • Cyproheptadine because it may decrease Effexor XR's effectiveness
  • Aripiprazole, haloperidol, phenothiazines (eg, chlorpromazine, thioridazine), or risperidone because the risk of their side effects may be increased by Effexor XR.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Effexor XR may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Effexor XR may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Effexor XR with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Effexor XR without checking with your doctor; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Several weeks may pass before your symptoms improve. Do NOT take more than the recommended dose, or use for longer than prescribed without checking with your doctor.
  • Children, teenagers, and young adults who take Effexor XR may be at increased risk for suicidal thoughts or actions. Watch all patients who take Effexor XR closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
  • Serotonin syndrome is a possibly fatal syndrome that can be caused by Effexor XR. Your risk may be greater if you take Effexor XR with certain other medicines (eg, "triptans," MAOIs, SSRIs). Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.
  • Neuroleptic malignant syndrome (NMS) is a possibly fatal syndrome that can be caused by Effexor XR. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Contact your doctor at once if you have any of these symptoms.
  • If your doctor tells you to stop taking Effexor XR, you will need to wait for a period of time before beginning to take certain other medicines (eg, MAOIs, nefazodone, thioridazine). Ask your doctor when you should start to take your new medicines after you have stopped taking Effexor XR.
  • Effexor XR may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
  • Lab tests, including blood pressure and blood cholesterol levels, may be performed while you use Effexor XR. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Effexor XR with caution in the elderly; they may be more sensitive to its effects, especially low blood sodium levels.
  • Caution is advised when using Effexor XR in children; they may be more sensitive to its effects, especially increased risk of suicidal thoughts or actions.
  • Effexor XR should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
  • Effexor XR may cause weight changes and growth changes. Children and teenagers may need regular weight and growth checks while they take Effexor XR.

Pregnancy and breast-feeding: Effexor XR may cause harm to the fetus if it is used during the last 3 months of pregnancy. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Effexor XR while you are pregnant. Effexor XR is found in breast milk. Do not breastfeed while taking Effexor XR.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Abnormal dreams; blurred vision; changes in taste; constipation; decreased sexual desire or ability; dizziness; drowsiness; dry mouth; flushing; headache; increased sweating; loss of appetite; nausea; nervousness; stomach upset; trouble sleeping; vomiting; weakness; weight loss; yawning.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bizarre behavior; blood in the stool; chest pain or discomfort; confusion; decreased concentration; decreased coordination; decreased urination; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; memory problems; new or worsening aggressiveness, agitation, anxiety, hostility, impulsiveness, inability to sit still, irritability, panic attacks, or restlessness; persistent or severe ringing in the ears; red, swollen, blistered, or peeling skin; seizures; severe or persistent anxiety, nervousness, or trouble sleeping; severe or persistent cough; severe or persistent headache, dizziness, stomach pain, or weakness; shortness of breath; significant weight loss; suicidal thoughts or attempts; tremor; trouble concentrating; unsteadiness or loss of coordination; unusual bruising or bleeding; unusual or severe mental or mood changes; unusual weakness; vision problems; worsening of depression.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

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